Introduction
Avian influenza A viruses continue to represent a major threat to global public health, animal health, food security, and economic stability. Emerging and re-emerging subtypes such as H5N1, H9N2, H10N3, and H5N9 demonstrate a significant capacity for rapid evolution, genetic reassortment, interspecies transmission, and adaptation to humans. While some strains cause severe disease and high mortality in humans, others circulate silently in poultry and wild birds, creating reservoirs that may facilitate the emergence of future pandemic variants.
The increasing complexity of influenza surveillance requires innovative and interdisciplinary approaches that integrate virology, epidemiology, veterinary science, environmental monitoring, genomics, and computational intelligence. In this context, artificial intelligence (AI) has emerged as a transformative tool for improving disease surveillance, outbreak prediction, genomic analysis, and public health preparedness. Machine learning algorithms, predictive modeling, data mining, and AI-assisted analytics can help identify patterns in viral evolution, detect early warning signals of outbreaks, and support rapid decision-making during health emergencies.
This edited volume, AI-Enabled Monitoring of Avian Influenza for Human Health and Global Preparedness, aims to provide a comprehensive and forward-looking exploration of emerging avian influenza viruses and the growing role of AI-driven technologies in influenza monitoring and pandemic preparedness. The book will examine the biological, ecological, epidemiological, and computational dimensions of avian influenza while emphasizing One Health approaches that integrate human, animal, and environmental health data.
By bringing together contributions from experts in infectious diseases, public health, veterinary medicine, computational biology, genomics, and AI research, this book seeks to establish an interdisciplinary platform for discussing current advances, challenges, and future directions in AI-enabled influenza preparedness and global health security.